FYI
I have posted before and seen other post on an intermittent issue where you get a Check Air Conditioner message when starting an RX350. Turning off the A/C and then back on seems to fix it.

I took my RX350 in for its first service and told them about the A/C problem. They confirmed there is a known issue and they ordered a $400 part (under warranty) to fix the problem. They should have it in and installed next week.

 

Yes, they just issued a TSIB for this problem.
http://www.alldata.com/tsb/Lexus/116...-06/index.html

 

Subscribing....thanks for the info!

 

Is anyone having "odor" issues with their AC? Mine seems to have a musty smell when it is first turned on. Have reported it to the dealership and they sprayed some stuff, but it doesn't seem to work. I'd hate to have one of "those cars" without fresh AC (or fresh air)
Anyone else?

 

I had my RX350 in yesterday for the 5,000 mile service and I had the TSIB for the A/C performed since the error had occurred a couple of times. They replaced the A/C amplifier assembly. Since we are now out of the A/C season I have no way of concluding if this fixed the problem.

 

It is a good idea to run the air conditioner for five or ten minutes every month.

This keeps the compressor seals flexible and the expansion valve operating smoothly.

 

Have you tried replacing your cabin filter? The one on my '06 330 was dirty but not saturated. Took me 10 minutes to figure out how to get to it, and less than 10 to take it out, clean it and reinstall.
Gary