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You're not going to get a lot of responses here about wheel offset. Nobody knows anything about it or cares.
Your best bet is call the place where you're purchasing from and ask them which is proper fitment for what you're trying to do and the look you're after.
To reference, these are my wheel offset for my Weds Mav 709M which are very similiar to your Work Zistance. Albeit, I didn't go as wide as I didn't want to do any major fender work on mine. With 9.5 F and 10.5 R you will have to roll or shave your fender liner. Mine is already having minor rub when I hit a dip or carry heavy passengers...thank goodness my kids are still small and I rarely carry adult passengers.
F: 20 X 9 +37 H-Disk Reverse Rim
R: 20 x 10 +42 L-Disk Reverse Rim
I have 20x9 +32 R-disk and 20x10.5 +45 A-disk. 245/35/20 and 285/30/20. fronts rub slightly if I hit a dip too hard. Got my rear fenders rolled to fit 285/30
Hey D1GP, I think I met you at Platinum VIP the other night, there can't be another person with a set of Zistance with the same specs haha.
My wheel's specs are: Work Zeast 2 20x8.5 +35 R-Disk 20x10 +40 H-disk
Pilot Sport 4S 245/35 20 275/30 20
Aired out, I rub in the front on dips on the freeway, and making left turns through intersection into dips. I think it's mostly the square tires though. I originally wasn't planning on cups or going that low.
I've attached a spreadsheet I made to calculate wheel specs to see how each setup compared to each other. The current specs in there were collected from threads where people said they got the setup to work, so it's labeled "works". Your Zistance set is highlighted in green. My current wheels are highlighted in yellow.