04 RX 330.

About a week ago, the car died on my wife. The instrument panel was working but nothing else, no radio, windows, steering column, etc. We replaced the battery and had the same problem with the new battery.

Working through all the fuses & relays, I discover the main fuse, 140amp fuse link, had gone bad. The fuse is bolted on the sides with an 8mm and a 10mm bolt. After taking the fuse box apart, to be able to get to the bolts and remove the fuse, I replaced the fuse, which happens to be a factory only fuse, couldn't find it at any local auto parts stores or amazon, the car started. I have windows, steering column, radio, chair, etc. The only thing not working now is the navigation screen, which also controls the AC/Heat, and the back up camera.

Any suggestions? I've gone through the manual and have checked every fuse that has any reference to nav screen.

 

Update:

I've triple checked the fuses and confirmed that they are all good. I have changed the fuses, regardless of the fact that they are all good, with no luck. I checked the fuse ports themselves to confirm that they are getting power, and it looks like they are.
I don't know how much power the ports are supposed to get, but they are hot and under the fuse threshold.
I called Lexus to see if they've had any experience, and they suggested I change the fuses.

Anyone come across something like this? Any suggestions?

 

Check for trouble codes. The navigation will throw a code if malfunctioning.

 

Thank you for the reply Rainbird.

Did that too. Nothing showing up on the OBD.