I was wondering the fluids that need replacement during the life of the NX350h
Other than the typical engine oil every 16k km, from Lexus' maintenance schedule, I can see the following fluids also should be replaced at those intervals (based on distance).

Brake Fluid Replacement @ 48k km
Replace Super Long Life Coolant @ 160k km
Replace Inverter Coolant @ 240k km

Are there any other fluids that should be replaced during the life of the NX350h and at what mileage?
Such as Transmission fluid, etc....

 

Depends really on two main factors. 1) how long do you plan to keep it 2) how much do you care about your car.

If the answer is 1) quite a long while 2) Yes, very much. If so, then watch this for what you should really do:

 

The Car Care Nut does coolant changes (he has the video's), but he does not FLUSH the coolant. Thats one area I dont agree with. He will do a drain of the radiator and "maybe" the open the block petcock, but does indeed leave some old fluid in the system.
When I do the coolant changes, I will try to run several drain and fills to minimize the percentage left in the system.

Regarding the topic of Oil Changes (which has been discussed ad infinitum).... most folks only go with miles driven and not elapsed time. The drawback w using miles only is that a very long time can pass and adverse conditions such as short trips, especially in very cold weather will adversely compromise oil chemistry. Severe driving conditions is an issue ( again, just repeating what is already know on this forum)

 

I do what by manufacturer of my vehicle, oil manufacturer, and shop foreman with 21 years experience state over any YouTube marketer.
Every 10,000 miles oil
Every 30,000 miles brake fluid changed
Every 100,000 antifreeze flushed
Worked for me one million miles six Lexus's

 

After watching the video, in summary, his suggested interval of fluid changes are half of what Lexus recommends. Expect for Brake fluid, which is based on moisture test.

What I find interesting is Lexus service schedule (specifically for NX350h) has no mention of replacing the CVT transmission fluid and E-transaxle fluid.

 

I get why people would want to religiously follow the manufacturer's recommendations. I was that person too at one time, actually for a very long time. And I actually did reasonably ok doing so, but change is the only constant. This was my journey....

When I had my RX hybrid it said "lifetime" fluid for the eCVT too and I scoffed at other's saying its dumb to treat it as lifetime. Toyota/Lexus knows best I told myself. But slowly I became less trusting of the manufacturer recommendations. First, I started to realize that the maintenance schedule differed between Canada and the US. Let's see, if I drive 30 seconds over the Rainbow bridge at Niagara Falls suddenly I do need to change my CVT fluid, why? (the US still has conditional statements on when the CVT and rear motor fluid in the NX350h needs to be changed, no such mention in Canada). I also started to notice other differences in maintenance recommendations between North America and other countries as well. So these cars are pretty much identical yet where you drive them changes your maintenance schedule. Why? I get it, Canada doesn't get crazy hot in the summer like southern US or Australia, but we have our own challenges and still makes me wonder what role local country distributors (and their bean counters, marketing people, etc) make in deciding maintenance schedules. I began to think if its a good idea in some places, perhaps its not so crazy for it to be a good idea here too. I finally changed my CVT and rear motor fluid at about the 10 yr mark and it just made me feel a lot better spending a few hundred bucks on my (what once was) $C70,000 RX. Doing maintenance makes me feel better, doing exceptional maintenance is my drug of choice.

I also became less trusting of Toyota when they went thru their massive oil burning issue on their earlier 2AR engines. They know that engine has serious design issues and sucked it up they had to do a lot of expensive warranty claims, but noticed they would only do so if the engine burned a huge amount of oil. Not a lot, but a huge amount. Why? Well they knew those engines would destroy the catalytic converter so better fix the engine before we also have to warranty a cat as well, but the rest, string them along until they are out of warranty then its their problem. That's when I realized manufacturers term "lifetime" really refers only to the amount of time they are willing to offer a warranty, not the duration of time a vehicle can be made to last. I'm watching very closely what Toyota and Lexus do with their new V6 engine issues to see how they decide to handle it. Don't get me wrong, I'm still a big fan and believe they do a very decent job building quality vehicles, but somewhat based on how so very badly many other manufacturers seem to have completely messed up with their engine quality/reliability. I believe Toyota generally has good intentions, but man, lately their rep has taken huge hits with their emissions cheating (got some VW envy going on?) and such. I don't, not for a second, ever forget these guys collectively number one motive is shareholder value. Not trying to be a pessimist, just a realist.

Over last few years I also started to watch a lot of mechanics videos on YT. Wow, so many destroyed engines from poor maintenance. One after the other, after another, wrecked engines piling up from sloppy maintenance. Everyone of them, "change your oil people", "change your oil", over and over again. I realize these guys have an angle too, to drive up ad revenue for themselves, but still, no shortage of stories they have to tell. Toyota also went thru some hard times over owner's suing because of excessive oil sludge buildup. Toyota's response, these people aren't changing their oil often enough, its their fault. So you are saying to change your oil often, but not that often. Hmmm. Many of those people had proof they were following the minimum maintenance guidelines. As with all these things, certainly the truth lies in the middle so its tough to draw exact conclusions other than to say having a meticulous fluid change schedule has potential upside and no downside other than a few extra bucks spent keeping your super expensive car in top condition.

I also get it that when watching these mechanic videos like Car Care Nut, these guys tend to see the worst outcomes landing in their bay time and time again. Their opinions are going to be skewed because they have to fix over and over again the mess people create for themselves (but also the mess manufacturer's create sometimes too) that may not necessarily be representative of the average. But maintenance isn't binary, there is no guarantee where your car will last 30 yrs and 500,000miles if you do this, but it will only last 12 yrs and 200,000 miles if you do that instead. There are only probabilities. On average if you follow the standard recommendations, you'll likely get average results thru the average lifetime. For many people that's perfectly fine or even exceeds their needs. Its a choice. I personally am looking to do better than average. No guarantees, but I believe I'm skewing the probabilities in my favour.

 

All the fluid change 'numbers' are based on getting the car past the warranty period.

Its a good selling point to the customer when they tell you extra long fluid change intervals.

It only benefits the builder of the vehicle.

After warranty expires, your on your own.

 

I'm with you 100% on this. And as I read your your piece I thought to myself, as a general casual consensus electronics either are doomed for failure quite quickly if they have a operational defect, bad connection, faulty internals in a component when it was manufactured etc. Electrons are simple in their requirements to perform the task at hand. Either there's a 'good' circuit or 'NO' circuit, there endith the facts. Like my faulty blindspot monitor on my '22 it failed relatively quickly and was replaced under warranty. Thank you Lexus. But I'll bet that if your electronics (ok other than the cable gate type scenarios where the electrical connections are exposed to a terrible operating environment) make it past the warranty period they'll provide many years of service. My last car lasted over 14 years without a bulb or dash component failing, nothing electronic broke.

So where do you continue to generate post sale revenues? Torture your mechanical components just enough to make it past the warranty period then $ cha-ching, wring in the repairs of transmissions, differentials, cooling systems, engine sludge or bearing failures etc. They're relatively easy to fix for a technician, expensive, and you'll get a genuine 'oh so sorry not sorry' from the service manager. Who'll explain, yah but you're actual driving conditions all these years should have been treated as 'extreme' conditions because you experienced very cold and very hot temperatures - you mean like the 4 seasons we have been having in the northern hemisphere since the last ice age?

For the most part, other than poor engineering (not something Toyota is known for) poor manufacturing (ok Toyota has some recent black eye's with this but their response is no where near the likes of Kia and Hyundai dragging their feet for years before they issue a recall for 10+ year old cars with dread engines etc.) the only other major factor relies on good mechanical maintenance. Toyota / Lexus will gladly take your money to change out fluids and service other wear and tear items more frequently then their recommended intervals, and if there happens to be some total mechanical failures in the overall scheme of things for vehicle lifespans, that's good too and we won't be held responsible for that.