Yes.

Best stock (I've replaced my stock sub for a JL 10) system I've ever heard.

People are blown away by it all the time.

 

My first 460 I had the premium system and was very disappointed in how flat it sounded, I heard the ML before and knew how fantastic it sounded so I regretted taking it off my shortlist of options. I did not make that mistake again and made sure to get the ML and love it! Could one build a better aftermarket system of course but it won't be cheap, check out the LS ML articles below.

http://www.autospies.com/news/The-Ul...urround-20229/

http://www.edmunds.com/car-technolog...sound-off.html

 

I had the lexicon sound system in my old genesi and it sounded amazing, but compared to the Mark Levinson it sound like an 8-track (well prolly not that bad but you catch my drift)

 

The ML sound system is really really good. Much better than the Infiniti Bose system.
Other Lexus owners say there is no difference between ML and regular sound system.
The LS460 ML system is 1000X better than my wife's RX's.

 

I traded mine a year ago and I still talk about the stereo in the LS . My ISF has the ml system but it's not nearly as good