26k miles on my gs350, avg 26. and that's in LA fwy traffic

 

The lifetime average of my 450h is sitting at 26 MPG with about 75% city driving. Pure city is about 23+ with moderate pedal use, while highway is about 33+.

Definitely go for the 350 at least, it is a beast of an engine, and one would be hard pressed to find something more efficient. The only reason I got the 450h was to get AVS, more power, and to invest in the technology/show desire to Lexus.