Should I use anything on the moonroof rubber seal to maintain it? My RX300 is two years old and no leak yet. I don't know if I should just leave it alone or use some dressing on it. Thanks.

And what kind of grease should I use for the moonroof track?

 

On the moonroof seal, you might want to put a small amount of glycerin (just use astroglide, glycerin is impossible to find) It lightly conditions the rubber and makes it look slightly darker, like new.

 

Is the RX kept in a garage or outside Harrier? I usually have my moonroof tracks lubbed twice a year when I take the car to my mechanic for oil changes......he usually uses white lithium grease &/ or stuff like dura lube penetrating fluid (sort of like wd40 or liquid wrench) works well too. Some detailers use a very light coating of vasaline of rubber seal / weatherstripping once a year (usually before the cold winter months here in Canada) as it conditions, protects & prevents cracking.

 

It's garage-kept. Thanks for the tips.