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I am running 40 profile on my supra 17's. I have the TEIN CS coilovers and there is no wheel gap in the front, and the same in the rear. but then again i have coilovers... they are made to slam your car ...
Depending on the width, i'd try and stick with 40 series. I have 235 40 18s on mine right now and the gap is pretty distingished. I'm guessing the ideal size for the sc would be 245 40 or wider. I'm selling these wheels to get some 18x10s with 275s, i'll prob go with the 35 ratio with those due to the width.