I had a miss that would come and go. Check engine light came on and car was sputtering horrible. Codes said cylinder number 6 was misfiring. Replaced plugs and car ran great for 2 days misfiring again. Replaced coil pack on # 6 cylinder, no help. Replaced plug again no help. Any ideas?

 

you will have to post this in 3 gen gs, this is 2 gen gs
i belive there is tbs for misfiring in gs300 but more info in 3 gen gs forum

 

Even if you do have the dealership perform the "fix" all their doing is bandaging it up. Every single 2006 gs300 is going to have this problem and when it's fixed you'd be lucky to get another 70k out of the car, Those are words straight out of the service managers mouth. My car was 3 weeks out of the 9 years and corporate lexus told me they wouldn't do a single thing for me on my gs with 80k on it. There isn't an actual fix for the problem, the service manager told me he wouldn't perform the "fix" if I were paying out of pocket because it's only a temporary bandage. Bottom line, lexus sells garbage and doesn't back their product.