I have a 2014 is350 type F. I need to replace the tpms module. Anyone know where it is and how to get it out? Thank you

Welcome to the forum!

The TPMS ECU is located in the driver's c-pillar. You will need to remove the rear seat and the c-pillar trim to access it.
Maybe before you tackle replacing it, you could share what the issue is. I don't believe anyone has had to replace a TPMS ECU due to a failure, so just wondering if you're having an issue that is fixable without replacing the ECU.

The tire light flashes on the dash and all pressure numbers go away. Light stays on. Every now and then the light goes off and tire pressure numbers reappear.

When the TPMS system has a malfunction the TMPS light will stay on solid, and tire pressure readings will vanish and be replaced by "---". This is normal when the light is on.
If the vehicle is driven long enough with the TPMS light on solid, it will then start to flash.
In either case this would indicate a code is stored in the system.
The flashing light could indicate that 1 or more TPMS sensors is not being detected.
Aside from the wiring, there are 7 components in the system:

• 4 TPMS sensors
• 1 TPMS ECU
• 1 TPMS Driver
• 2 TPMS Receivers

All components eventually lead to the TPMS ECU, so there are multiple points of possible failures before the ECU.
I would suggest getting a code reader and find out what code(s) are there first. I use a Veepeak bluetooth off Amazon ($23 CAD) with the free CarScanner app. It can scan all computers in the vehicle.
This will tell you where the point of failure is so you can hopefully fix it right the first time...it could be as simple as a battery is going dead in one of the TPMS sensors.

You're welcome to replace the ECU first, but I'm highly doubtful that will fix anything...not to mention you will need to program all the sensors to it as well.
And without a tool or scanner to retrieve the TPMS sensor codes, you will need to take it to a shop for programming.

If only 1 tpms sensor is bad would it not read on the other 3?

Short answer...no.

Long answer...when a trouble code is set in the system, i.e. for a defective or dead sensor, the warning comes on and the system is disabled.
Therefore you will not get any sensor readings.
If you have a Techstream or the Veepeak tool (or something similar) that I mentioned, you will be able to see the pressures on the tool.
By letting some air out of each tire one at a time, that will tell you which sensor is defective...this is assuming you have a defective sensor.
With the tool you can get the trouble code, which would tell what the issue really is first, before you start checking anything.