02 Lexus GS300 with about 123k miles my driver doors lock acts up when I lock it with the remote it doesnt lock only the driver side... and when I disconnect the batter for 10 mins and hook it back on it seems to lock again with the remote... does anyone else have this problem?

 

Yeah.. Its all over the forums. You have a bad door actuator. Its going to get worse.

 

He's right. Its a bad actuator. Search in the DIY section if you plan to do it. Part's about $70 - $90 on the dealer. Really simple to do. It will get worse if you ignore it and give you more costly problems later.