Does anyone else have a problem hitting the garage door opener? When I drive home at night, I have to stop and look closely. My previous ES 330 had the same setup, and I could easily put my finger on the button.

 

Same problem here. I have opened the moon roof several times. Would have been nice if those buttons were illuminated.

 

My O2 ES was much easier. This is the only design area I have a problem with on the ES 350. It's too much concentration to try and hit the right button.

 

I've noticed my wife has a harder time than I pushing in the button with her longer finger nails. I know I should not compare, but, my Avalon has the Homelink on the bottom of the rearview mirror and #1 is the first button on the left so you can reach/feel/push without even looking at it.

 

I'm with TNFAN, those buttons should be illuminated. And yes, they are hard to activate, especially at night.