I was driving on the expressway in STL last year and saw the presidential motorcade flying the other direction on the highway. a VERY IMPRESSIVE sight to see. The whole motorcade was spaced out over about a mile it seemed. They closed off every on and off ramp in the direction he was traveling.

 

When he comes to Tampa and needs to cross one of the bridges, they'll close the bridge on its side as well. There are 3 bridges spread out evenly over 15 miles. So if they need to go to over the Howard Frankland(center bridge and biggest), then they close all 3 bridges. Which sucks because thats the only access to St. Pete and Clearwater.