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I hope this doesn't turn into Zaino vs Brand X discussion.
I think Zaino products are good, but not great. There's too much hype in their "sealant"...which eventually breaks down like any other wax on the market.
Check the maintenance forum for LOTS of good information on how to maintain Lexus's sealed leather.
And if your wife gets chewing gum all over her butt leaning up against a plant container at the airport then unknowingly sits in the passenger's seat, Goo-Gone will get it completely removed. AMHIK.