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Id suggest doing it every 30-50k. Especially do it when you're getting new spark plugs
Thanks so much for the advice! I found a local guy in the area to do it $600 CAD including new gaskets. I only have 125,000 kms and the amount of buildup was pretty astonishing. Clublexus should pin this thread as a PSA for IS250 owners seriously...
I don't feel much difference in performance but I wasn't having the obvious carbon buildup problems yet. I'll definitely keep this as a regular service for as long as I own the car.