We have a Peg Perego infant car seat that goes in the middle.
There's a base that is anchored using the LATCH.
Even, if you prefer to use the seat belts, i don't see any problem with space.
And my mother in law can sit on either side comfortably.
2013 Lexus RX 350 Silver Metallic
2013 Toyota RAV4 EV Blizzard Pearl
2013 Tesla model S p85 Pearl White
2010 Land Rover Range Rover HSE Fuji White