Just got an '09 LX a few months ago with 53K miles. It is/was a GREAT purchase! In 2003, I made a similar decision when I bought a '99 Land Cruiser with 50K miles on it. Drove it for 10 years and ran it up to 162K miles with ZERO issues! Thus, I'm using the same strategy.
If you're buying from an individual, I would do a pre-purchase inspection. It's the best $100 you'll spend. Also, be careful with options. For the 2008 and 2009, you'd be surprised to know that some of the "little things" are actually options (cool box, navigation, radar-controlled cruise control, and others). True, most people buying these cars new got them decked out nicely, but...even the "luxury package" doesn't guarantee everything.
As for price...I would guess that you should wind up in the low $40K's. Regardless, you will be thrilled with this vehicle. It is truly a FANTASTIC machine!