So although I don't have personal experience with this in my 2011 IS250, because it came with Bluetooth audio integration I feel your pain. In my truck and my Harley I bought 2 of these
As the above person mentioned just plug it into your aux input and turn it on. The sound quality is outstanding and has a great battery life. It is battery powered so you have to charge it every so often. But that's by micro USB which the vast majority of phones have today. As yoh can see its 90 degree angled so should fit in your center console without issues. That's it.