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I think the ISF will because it was the first F car but that really depends on what Lexus does with F over the next few decades. LFA is really the only one that is sure to get in and maybe the first LS400
I think only the LFA will be a collector car. I just don't see any of us, or our kids flipping out and spending big bucks on any other Lexus rolling down Barrett Jackson Auctions or other similar auctions in 20+ years.
the LFA of course. the first gen LS and GS if the ECU's hold up even after repair. the SC would, but there's too many raced out at the moment (see #sc300)